This special issue of Science, Technology and Human Values was guest edited by members of the AnNex team. It explores the changing situation of the 3Rs through five papers that explore how the 3Rs principles emerged, chart the ways they are enacted in practice, and reflect on their future challenges.
This Nature correspondence note, written by Gail Davies, explains the principles of the UK’s Animals in Science Committee (ASC) review of the processes of harm–benefit analysis (HBA) carried out under the UK Animals (Scientific Procedures) Act 1986 (ASPA).
Improving laboratory animal science and welfare involves many questions which social scientists and humanities scholars have researched, or have the capacity to inform. This paper outlines our “Collaborative Agenda for Future Humanities and Social Scientific Research on Laboratory Animal Science and